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Research ArticlePharmacognosy MagazineVol. 4 | Issue 13s | 2008 | pp. 112–114Open access
Analgesic effects of methanolic extract of Capparis zeylanica Linn. roots
- 1*,
- 1,
- 1,
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- 1 Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha 442 001 (M.S.), India.
Published in Pharmacognosy Magazine
Correspondence: A.B. Upaganlawar
Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha 442 001 (M.S.), India.
Email: amanrx@yahoo.com
Copyright: © 2008 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2008
How to cite
Upaganlawar, A., Chopade, V., Ghule, B., & Yeole, P. (2008). Analgesic effects of methanolic extract of Capparis zeylanica Linn. roots. Pharmacognosy Magazine, 4(13s), 112–114.
Abstract
The present study was aimed to investigate the analgesic effects of the methanolic extract of Capparis zeylanica Linn. (MECZ) roots in rats and mice. The MECZ (250- 500 mg/kg; p.o.) was evaluated for its analgesic activity by employing acetic acid-induced writhing test, hot plate test and tail immersion tests i.e. in hot and cold water. MECZ (250- 500 mg/kg; p.o.) showed significant (P<0.01) reduction in the number of writhing induced by acetic acid, increased reaction time in hot plate test and elevated pain threshold in hot and cold water tests. MECZ exhibited the dose-dependent analgesic effects. In addition, the acute toxicity studies revealed that MECZ has good margin of safety and did not show the lethal effects on the animals up to the doses of 4 g/kg.
Keywords
Subject
Article metadata
| Title | Analgesic effects of methanolic extract of Capparis zeylanica Linn. roots |
|---|---|
| Authors | A.B. Upaganlawar; V.V. Chopade; B.V. Ghule; P.G. Yeole |
| Affiliations | Institute of Pharmaceutical Education and Research, Borgaon (Meghe), Wardha 442 001 (M.S.), India. |
| Corresponding author | amanrx@yahoo.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 4, Issue 13s (2008) |
Also in this issue
- Standardization of a Polyherbal Formulationpp. 65–66
- In vitro antioxidant studies of Ficus racemosa Linn. rootpp. 70–71
- Pharmacognostical and Physico-chemical Standardization of Root of Eranthemum roseum. (Vahl) R.Br.pp. 75–76
- Diuretic activity of whole plant extracts of Cardiospermum halicacabum (linn)pp. 80–82
- Pharmacognostical studies of leaves of Machilus macrantha Nees.pp. 83–84
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