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Research ArticlePharmacognosy MagazineVol. 5 | Issue 17 | 2009 | pp. 28–36Open access
Chemical Composition and Hepato-protective activity of Imperata cylindrica Beauv.
- 1,
- 2,
- 3,
- 4,
- 4*,
- 4
- 1 Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.
- 2 Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.
- 3 Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
- 4 Faculty of Environmental Earth Science, Hokkaido University, Sapporo, 060-0810, Japan.
Published in Pharmacognosy Magazine
Correspondence: Ehab S. Elkhayat
Faculty of Environmental Earth Science, Hokkaido University, Sapporo, 060-0810, Japan.
Email: khayat71@yahoo.com
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- May 10, 2008
- Accepted:
- Aug 2, 2008
How to cite
Mohamed, G. A., Abdel-Lateff, A., Fouad, M. A., Ibrahim, S. R. M., Elkhayat, E. S., & Okino, T. (2009). Chemical Composition and Hepato-protective activity of Imperata cylindrica Beauv. Pharmacognosy Magazine, 5(17), 28–36.
Abstract
Phytochemical study of the aerial parts of Imperata cylindrica Beauv. (Graminae), growing in Egypt afforded four methoxylated flavonoids 1-4, β-sitosterol-3-O-β-D-glucopyranosyl-6´-tetradecanoate 5, 3-hydroxy-4-methoxy-benzaldehyde 6, together with daucosterol, β-sitosterol and α-amyrin 7-9. To the best of our knowledge, this is the first isolation of compounds 1-5 from the genus Imperata. A significant hepato-protective activity had been observed upon co-administration of the methanolic extracts of I. cylindrica with CCl4. The structures were determined using spectroscopic data; 1D (1H and 13C), 2D (HSQC, and HMBC) NMR; MS; UV and IR.
Keywords
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Article metadata
| Title | Chemical Composition and Hepato-protective activity of Imperata cylindrica Beauv. |
|---|---|
| Authors | Gamal A. Mohamed; Ahmed Abdel-Lateff; Mostafa A. Fouad; Sabrin R. M. Ibrahim; Ehab S. Elkhayat; Tatsufumi Okino |
| Affiliations | Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.; Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Faculty of Environmental Earth Science, Hokkaido University, Sapporo, 060-0810, Japan. |
| Corresponding author | khayat71@yahoo.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 5, Issue 17 (2009) |
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