Open access · Peer reviewed · No APCs
Research ArticlePharmacognosy MagazineVol. 5 | Issue 19s | 2009 | pp. 11–14Open access
Hypolipidemic activity of gum ghatti of Anogeissus latifolia.
- 1,
- 2*,
- 3,
- 2,
- 4
- 1 Department of Biotechnology, S.R.N.M. National College of Applied Sciences, Shivamogga, Karnataka, India-577201, India.
- 2 Department of P.G. studies in Biotechnology, Sahyadri Science College (Autonomous), Kuvempu University, Shivamogga-577203, Karnataka, India.
- 3 Department of P G studies in Biotechnology and Bioinformatics, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Shivamogga (D.) Karnataka, India-577541, India.
- 4 Department of Pharmacology, National Pharmacy College, Shivamogga, Karnataka, India-577201, India.
Published in Pharmacognosy Magazine
Correspondence: Ramesh C. K.
Department of P.G. studies in Biotechnology, Sahyadri Science College (Autonomous), Kuvempu University, Shivamogga-577203, Karnataka, India.
Email: ckramck@yahoo.co.in
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Mar 23, 2009
- Accepted:
- Jun 15, 2009
How to cite
K.M.M., P., K., R. C., V., K., M., P., & I.J., K. (2009). Hypolipidemic activity of gum ghatti of Anogeissus latifolia. Pharmacognosy Magazine, 5(19s), 11–14.
Abstract
Cardiovascular diseases are becoming an increasing problem worldwide and hypercholesterolemia has been correlated for coronary heart diseases. Currently available hypolipidemic drugs have been associated with number of side effects. Herbal treatment for hyperlipidemia poses no side effects and is relatively cheap and locally available. In view of this, the present study was carried out to investigate the effect of gum ghatti of Anogeissus lalifolia on serum lipid levels of albino rats. Rats were made hyperlipidemic by the oral administration of cholesterol (400mg/kg body weight/day) along with cholic acid (50mg/kg) in coconut oil. The hypolipidemic effect was compared with control. The rats were divided into six groups of six animals each. In atherogenic diet induced hyperlipidemic model, the rats receiving treatment with gum ghatti at 250 mg/kg dosage showed significant reduction in serum triglyceride (82.75±0.63) only and there was no significant changes either in serum total cholesterol or elevation in HDL. Whereas, at 500 and 750 mg/kg dosage showed significant reduction in serum total cholesterol (72.85±0.60, 68.17±0.95) and serum triglyceride (78.92±0.34, 75.93±1.05). Further, the 750 mg/kg dose has also exhibited significant elevation in high density lipoprotein cholesterol (41.13±0.37).
Keywords
Subject
Article metadata
| Title | Hypolipidemic activity of gum ghatti of Anogeissus latifolia. |
|---|---|
| Authors | Parvathi K.M.M.; Ramesh C. K.; Krishna V.; Paramesha M.; Kuppast I.J. |
| Affiliations | Department of Biotechnology, S.R.N.M. National College of Applied Sciences, Shivamogga, Karnataka, India-577201, India.; Department of P.G. studies in Biotechnology, Sahyadri Science College (Autonomous), Kuvempu University, Shivamogga-577203, Karnataka, India.; Department of P G studies in Biotechnology and Bioinformatics, Kuvempu University, Jnana Sahyadri, Shankaraghatta, Shivamogga (D.) Karnataka, India-577541, India.; Department of Pharmacology, National Pharmacy College, Shivamogga, Karnataka, India-577201, India. |
| Corresponding author | ckramck@yahoo.co.in |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 5, Issue 19s (2009) |
Also in this issue
- Antihyperglycemic and antioxidant effects of Talinum portulacifolium leaf extracts in streptozotocin diabetic rats: A dose-dependent studypp. 1–10
- Occurrence of high levels of Cadmium, Mercury and Lead in Medicinal Plants of Indiapp. 15–18
- Phytochemical and anti-ulcer investigations of the whole plant extract of Neregamia alata Wight & Arn. in albino rat model.pp. 19–22
- Antidiarrheal Activity of Cynodon Dactylon. pers.pp. 23–27
- Studies on diuretic and laxative activity of bark extracts of Spondias pinnata (Linn. f) Kurzpp. 28–31
Readers Also Viewed
Effect of the Fractions of Coccinia grandis on Ethanol- Induced Cerebral Oxidative Stress in Rats
M. Umamaheswari, T. K. Chatterjee
Jan 1, 2009
Phytochemical Screening and Antioxidant Activity Evaluation of Selected Philippine Fruit Peels and Pulps
Mildred Dagcuta Pates, Angelo Mark Po Walag, Romeo M. Del Rosario
Aug 17, 2026
Impact of Artificial Intelligence Assisted Drug Therapy Optimization on Drug Related Problems Amongst Older Adult Patients: A Systematic Review
Jehath Syed, Christy Thomas, Bavneet Kaur
Oct 23, 2026