Open access · Peer reviewed · No APCs
Research ArticlePharmacognosy MagazineVol. 5 | Issue 20 | 2009 | pp. 301–305Open access
Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens) in Rats
- 1,
- 2,
- 3,
- 4*
- 1 Department of Biological Sciences, Faculty of Science, Al al-bayt University, Mafraq-Jordan, Jordan.
- 2 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alfateh University of Medical Sciences, Tripoli, P.O.Box 13620, Libya.
- 3 Department of Biological Sciences, Faculty of Science, University of Jordan, Amman 11942 Jordan, Jordan.
- 4 Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942 Jordan, Jordan.
Published in Pharmacognosy Magazine
Correspondence: Aburjai Talal
Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942 Jordan, Jordan.
Email: aburjai@ju.edu.jo
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Apr 2, 2009
- Accepted:
- Jun 8, 2009
How to cite
Kamal, M., M, A. A., Ahmad, D., & Talal, A. (2009). Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens) in Rats. Pharmacognosy Magazine, 5(20), 301–305.
Abstract
The hypolipidemic effects of ethanol extract of A. graveolens L. (Apiaceae) were investigated. Forty adult male albino rats weighing about 260 g each, were divided into four groups (n = 10). Experimental animals were gavaged at doses of 213 and 425 mg/kg body wt. for sixty consecutive days. Extract showed a significant decrease (p<0.05) of serum total cholesterol, triglycerides, low-density lipoprotein cholesterol (LDL-c), and significant increase (p<0.05) in high-density lipoprotein cholesterol (HDL-c) in the treated groups. The oral administration of ethanol extract of A. graveolens revealed good hypolipideamic effects in adult male albino rats. The results have given a considerable agreement to the traditional use of A. graveolens in the treatment of hyperlipidemia; it could possibly lead to appropriate changes in blood lipid profiles.
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Article metadata
| Title | Hypolipidemic Effects of Seed Extract of Celery (Apium graveolens) in Rats |
|---|---|
| Authors | Mansi Kamal; Abushoffa Adel M; Disi Ahmad; Aburjai Talal |
| Affiliations | Department of Biological Sciences, Faculty of Science, Al al-bayt University, Mafraq-Jordan, Jordan.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alfateh University of Medical Sciences, Tripoli, P.O.Box 13620, Libya.; Department of Biological Sciences, Faculty of Science, University of Jordan, Amman 11942 Jordan, Jordan.; Department of Pharmaceutical Sciences, Faculty of Pharmacy, University of Jordan, Amman 11942 Jordan, Jordan. |
| Corresponding author | aburjai@ju.edu.jo |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 5, Issue 20 (2009) |
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