Open access · Peer reviewed · No APCs
Case ReportJournal of Pharmacology and PharmacotherapeuticsVol. 11 | Issue 2 | 2020 | pp. 75–7Open access
Ticagrelor-Induced Complete Heart Block: A Rare Entity
- 1,
- 1*,
- 2,
- 2,
- 1
- 1 Department of Pharmacology Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
- 2 Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Published in Journal of Pharmacology and Pharmacotherapeutics
Correspondence: Isha Khadke
Department of Pharmacology Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Email: ishakhadke@gmail.com
Copyright: © 2020 Manuscript Technomedia LLP. This is an open access article.
- Published:
- Oct 21, 2020
- Received:
- Dec 14, 2019
- Accepted:
- Jul 28, 2020
How to cite
Anand, W. V., Khadke, I., Padmakumar, R., Rao, M. S., & Chogtu, B. (2020). Ticagrelor-Induced Complete Heart Block: A Rare Entity. Journal of Pharmacology and Pharmacotherapeutics, 11(2), 75–7. https://doi.org/10.4103/jpp.JPP_121_19
Abstract
Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor.
Keywords
Subject
Article metadata
| Title | Ticagrelor-Induced Complete Heart Block: A Rare Entity |
|---|---|
| Authors | Wagle Varun Anand; Isha Khadke; R Padmakumar; M Sudhakar Rao; Bharti Chogtu |
| Affiliations | Department of Pharmacology Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India.; Department of Cardiology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India. |
| Corresponding author | ishakhadke@gmail.com |
| Journal | Journal of Pharmacology and Pharmacotherapeutics |
| Volume / Issue | Vol. 11, Issue 2 (2020) |
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