Ganciclovir–tenofovir interaction leading to tenofovir‑induced nephrotoxicity

Soanker, Radhika; Udutha, Shobha Jagdish Chandra; Subbalaxmi, Malladi V S; Raju, YSN

doi:10.4103/0976-500X.142452

Case ReportJournal of Pharmacology and PharmacotherapeuticsVol. 5 | Issue 4 | 2014 | pp. 265–267Open access

Ganciclovir–tenofovir interaction leading to tenofovir‑induced nephrotoxicity

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¹ Departments of Clinical Pharmacology and Therapeutics, Institute of Medical Sciences, Hyderabad, Telangana, India.
² General Medicine, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India.

Correspondence: Radhika Soanker
Departments of Clinical Pharmacology and Therapeutics, Institute of Medical Sciences, Hyderabad, Telangana, India.

Published:: Jan 1, 2014
Received:: Dec 30, 2013
Accepted:: Apr 25, 2014
DOI:: 10.4103/0976-500X.142452

How to cite

Soanker, R., Udutha, S. J. C., Subbalaxmi, M. V. S., & Raju, Y. (2014). Ganciclovir–tenofovir interaction leading to tenofovir‑induced nephrotoxicity. Journal of Pharmacology and Pharmacotherapeutics, 5(4), 265–267. https://doi.org/10.4103/0976-500X.142452

Abstract

Viral enteritis is an important gastrointestinal disorder in human immunodeficiency virus (HIV)‑infected patients. Cytomegalovirus (CMV) is the most common opportunistic agent in these patients. As ganciclovir and tenofovir are the most commonly used drugs for the treatment of CMV and HIV infection, respectively, this case report showcases the potentiality of drug interaction as well as the safety measures to be taken when using these two drugs together in unavoidable situations.

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Article metadata

Title	Ganciclovir–tenofovir interaction leading to tenofovir‑induced nephrotoxicity
Authors	Radhika Soanker; Shobha Jagdish Chandra Udutha; Malladi V S Subbalaxmi; YSN Raju
Affiliations	Departments of Clinical Pharmacology and Therapeutics, Institute of Medical Sciences, Hyderabad, Telangana, India.; General Medicine, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India.
Journal	Journal of Pharmacology and Pharmacotherapeutics
Volume / Issue	Vol. 5, Issue 4 (2014)