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Research ArticlePharmacognosy ResearchVol. 1 | Issue 3 | 2009 | pp. 125–129Open access
Biological activity of Crambe orientalis L. growing in Iran
- 1*,
- 2,
- 1,
- 1,
- 1
- 1 Department of Biology, University of Mohaghegh Ardabili, Ardabil, Iran.
- 2 Depatrment of Animal Sciences, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran
Published in Pharmacognosy Research
Correspondence: S. M. Razavi
Department of Biology, University of Mohaghegh Ardabili, Ardabil, Iran.
Email: razavi694@gmail.com
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Mar 10, 2009
- Accepted:
- Apr 9, 2009
How to cite
Razavi, S. M., Zarrini, G., Zahri, S., Ghasemi, K., & Mohammadi, S. (2009). Biological activity of Crambe orientalis L. growing in Iran. Pharmacognosy Research, 1(3), 125–129.
Abstract
Crambe orientalis (Brassicaceae) is a perennial herb growing wild in Iran. Cytotoxic, antioxidant, antimicrobial and phytotoxic effects of the plant leaves extracts have been evaluated by MTT, DPPH, Disc diffusion and lettuce assays, respectively. Our results showed that dichloromethane and methanol extracts of the plant leaves exhibited high cytotoxic effects against Mc-Coy cell line with IC50 value of 659 and 432 µg/ml, respectively. The extracts indicated high antioxidant activity with RC50 value of 33.3 and 40.5 µg/ml, respectively. Methanol extract showed strong antibacterial activity against both gram-positive and gram-negative bacteria. All the extracts displayed significant allelopatic potential, as well as. It is assumed that biological activity of the plant may be related to presence of isothiocyanates in the plant leaves.
Keywords
Subject
Article metadata
| Title | Biological activity of Crambe orientalis L. growing in Iran |
|---|---|
| Authors | S. M. Razavi; G. Zarrini; S. Zahri; K. Ghasemi; S. Mohammadi |
| Affiliations | Department of Biology, University of Mohaghegh Ardabili, Ardabil, Iran.; Depatrment of Animal Sciences, Faculty of Natural Sciences, University of Tabriz, Tabriz, Iran |
| Corresponding author | razavi694@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 1, Issue 3 (2009) |
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- Proximate and qualitative analysis of different parts of Piper sarmentosum, and quantification of total amides in various extractspp. 113–119
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