Study of Antibacterial Activity and Phytochemical Screening of Two Selected Ethnobotanical Plants of Asteraceae from West Bengal, India

The objectives of the present study were to evaluate the quantitative and qualitative analysis of some phytochemicals and antibacterial properties of two medicinal plants Glossocardia bidens (Retz.) Veldkamp and Grangea maderaspaterna (L.) L poir under Asteraceae family from Purulia, West Bengal, India. Preliminary phytochemical analysis (alkaloids, carbohydrates, flavonoids, phenol, phlobatannins, saponin, terpenoids, and tannin) and quantitative analysis of total phenolic content and total flavonoid content were done by using appropriate experimental protocols according to the standard methods found in literature study. The antibacterial activity was observed using agar well diffusion method. Determination of Minimum Inhibitory Concentration (MIC) was also done to detect that concentration which showed complete bacterial growth inhibition. The preliminary phytotochemical analysis of these two experimental plants revealed the presence of the secondary metabolites such as alkaloids, carbohydrates, flavonoids, phenol, phlobatannins, saponin, terpenoids, and tannin in ethanolic extract. The estimation of total phenol and flavonoid content in the ethanolic root extract of Glossocardia bidens (Retz.) Veldkamp and the ethanolic leaf extract of Grangea maderaspaterna (L.) L poir also showed good results. The antibacterial activity test showed good results in the ethanolic root extract of Glossocardia bidens (Retz.) Veldkamp and ethanolic leaf extract of Grangea maderaspaterna (L.) L poir.