GC-MS Based Phytochemical Profiling and Pharmacological Evaluation of Cynodon dactylon (Durva) Extracted in a Sesame Oil (Tila Taila) Base

Background

Durva Taila is a classical Ayurvedic formulation prepared by processing the fresh juice of Durva (Cynodon dactylon) in Tila Taila (Sesamum indicum oil). It has long been utilized to treat inflammatory diseases, bleeding disorders, and wounds. Its chemical components’ scientific evaluation aids in bridging the gap between conventional wisdom and contemporary pharmacology.

Objectives

To analyze the chemical composition of Durva Taila prepared in Tila Taila base using Gas Chromatography–Mass Spectrometry (GC-MS).

Materials and Methods

Durva Taila was prepared according to the classical Ayurvedic Taila Paka procedure, using Tila Taila as the base. The prepared formulation was analyzed by Gas Chromatography–Mass Spectrometry (GC-MS), and the chemical constituents were identified by comparing the obtained mass spectra with those available in the NIST library. Results: The analysis revealed the existence of various phytoconstituents, such as fatty acid, esters, hydrocarbons and phytosterols. The principal compounds identified were 2,4-Decadienal, Palmitic Acid, Decanal, Phytol, Erucic acid, β-Sitosterol acetate. These components have been found to have anti-inflammatory, antioxidant, antimicrobial, wound-healing, and haemostatic effects. Conclusion: The GC-MS profiling of Durva Taila, formulated in a Tila Taila base, indicated the existence of various bioactive compounds consistent with its conventional therapeutic uses.