Open access · Peer reviewed · No APCs
Review ArticlePharmacognosy ResearchVol. 18 | Issue 4 | 2026 | pp. 1195–1205Open access
Bioactive Secondary Metabolites of Allium fistulosum L.: Nutraceutical and Pharmacological Implications
- 1,
- 2,
- 2*,
- 3,
- 4,
- 2,
- 5,
- 6,
- 7,
- 8
- 1 Department of Chemistry ITM University, Gwalior, Madhya Pradesh, INDIA
- 2 Department of Pharmacology, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, INDIA.
- 3 Department of Pharmaceutics ,Hitkarni college of Pharmacy Dumna Road Jabalpur, INDIA
- 4 Department of Pharmaceutics, Shri Rawatpura Sarkar College Sagar, Education Center in Sagar, Madhya Pradesh, INDIA.
- 5 Department of Pharmaceutics, Dr Anar Singh College of Pharmacy, Farrukhabad, Uttar Pradesh, INDIA.
- 6 Department of Pharmaceutics, Faculty of Pharmacy Major SD Singh University, Farrukhabad, Uttar Pradesh, INDIA.
- 7 Department of Pharmaceutics, Shri Sahaj Institute of Pharmacy, Khargone, Madhya Pradesh, INDIA.
- 8 Department of Pharmaceutics, Shri Ram Group of Institutions, Faculty of Pharmacy, Jabalpur, Madhya Pradesh, INDIA.
Published in Pharmacognosy Research
Correspondence: Shubham Anand
Department of Pharmacology, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, INDIA.
Email: anandshubham582@gmail.com
Copyright: © 2026 Manuscript Technomedia. This is an open access article.
- Published:
- Aug 30, 2026
- Received:
- Jan 19, 2026
- Accepted:
- May 21, 2026
How to cite
Kothari, R., goyal, A., Anand, S., Shukla, K., Sharma, A., Raikwar, H., Bardiya, P., Bhadouriya, D. S., Rewapati, S., & Shivavedi, N. (2026). Bioactive Secondary Metabolites of Allium fistulosum L.: Nutraceutical and Pharmacological Implications. Pharmacognosy Research, 18(4), 1195–1205. https://doi.org/10.5530/pres.20260037
Abstract
Background and Objectives
Allium fistulosum L. (spring onion), a member of the Amaryllidaceae family, is valued for its nutritional and therapeutic properties. This review aims to summarize its phytochemical composition, pharmacological activities, and potential applications in nutraceuticals, pharmaceuticals, and functional foods.
Materials and Methods
A comprehensive literature search was conducted using Google Scholar, PubMed, Scopus, and ScienceDirect. Botanical identification was verified through The Plant List, and chemical structures were confirmed using PubChem and peer-reviewed sources. Relevant in vitro, in vivo, and clinical studies were analyzed.
Results
A. fistulosum contains sulfur-containing compounds, flavonoids, phenolic acids, phytosterols, and saponins. These bioactive constituents exhibit antioxidant, anti-inflammatory, antimicrobial, and anticancer activities. Mechanistically, they modulate oxidative stress, inflammatory mediators, and metabolic pathways, contributing to reduced risk of chronic diseases such as cancer, diabetes, and cardiovascular disorders.
Conclusion
Allium fistulosum is a promising natural source of bioactive secondary metabolites with significant therapeutic potential. However, further molecular studies, standardization strategies, and well-designed clinical trials are necessary to support its translational application in health-promoting products.
Keywords
Subject
Article metadata
| Title | Bioactive Secondary Metabolites of Allium fistulosum L.: Nutraceutical and Pharmacological Implications |
|---|---|
| Authors | Richa Kothari; Amrita goyal; Shubham Anand; Kavita Shukla; Ankita Sharma; Harsha Raikwar; Pushpendar Bardiya; Deep Singh Bhadouriya; Shivpal Rewapati; Naveen Shivavedi |
| Affiliations | Department of Chemistry ITM University, Gwalior, Madhya Pradesh, INDIA; Department of Pharmacology, School of Pharmacy, ITM University, Gwalior, Madhya Pradesh, INDIA.; Department of Pharmaceutics ,Hitkarni college of Pharmacy Dumna Road Jabalpur, INDIA; Department of Pharmaceutics, Shri Rawatpura Sarkar College Sagar, Education Center in Sagar, Madhya Pradesh, INDIA.; Department of Pharmaceutics, Dr Anar Singh College of Pharmacy, Farrukhabad, Uttar Pradesh, INDIA.; Department of Pharmaceutics, Faculty of Pharmacy Major SD Singh University, Farrukhabad, Uttar Pradesh, INDIA.; Department of Pharmaceutics, Shri Sahaj Institute of Pharmacy, Khargone, Madhya Pradesh, INDIA.; Department of Pharmaceutics, Shri Ram Group of Institutions, Faculty of Pharmacy, Jabalpur, Madhya Pradesh, INDIA. |
| Corresponding author | anandshubham582@gmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 18, Issue 4 (2026) |
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