Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy ResearchVol. 2 | Issue 6 | 2010 | pp. 359–363Open access
Modulating effect of Gmelina arborea Linn. on immunosuppressed albino rats
- 1*,
- 2,
- 3
- 1 Indukaka Ipcowala College of Pharmacy, New Vallabh Vidyanagar, Dist. Anand, Gujarat - 388 121
- 2 A.R.College of Pharmacy, Vallabh Vidyanagar, Dist. Anand, Gujarat - 388 120
- 3 Nutan Education Trust’s B. Pharmacy College, At. Rampura, Po. Kakanpur, Tal. Godhra, Dist. Panchmahal, Gujarat - 389 713, India
Published in Pharmacognosy Research
Correspondence: S. H. Shukla
Indukaka Ipcowala College of Pharmacy, New Vallabh Vidyanagar, Dist. Anand, Gujarat - 388 121
Email: shshukla@rediffmail.com
Copyright: © 2010 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2010
- Received:
- Jun 27, 2010
- Accepted:
- Jan 12, 2011
How to cite
Shukla, S. H., Saluja, A. K., & Pandya, S. S. (2010). Modulating effect of Gmelina arborea Linn. on immunosuppressed albino rats. Pharmacognosy Research, 2(6), 359–363. https://doi.org/10.4103/0974-8490.75455
Abstract
Aim
In the present study, the immunomodulatory effects of roots of Gmelina arborea Linn. were investigated.
Materials and Methods
Methanolic extract of G. arborea Linn. (MEGA) and its ethyl acetate fraction (EAFME) were used for evaluating the pharmacological activity. The modulating effect was evaluated on humoral and cell-mediated immune response using animal models like cyclophosphamide-induced myelosuppression, delayed-type hypersensitivity (DTH) response, and humoral antibody (HA) titre.
Results
Both test extracts produced significant increase in HA titre, DTH response, and levels of total white blood cell count.
Conclusion
This drug is found to be a potential immunostimulant.
Keywords
Subject
Article metadata
| Title | Modulating effect of Gmelina arborea Linn. on immunosuppressed albino rats |
|---|---|
| Authors | S. H. Shukla; A. K. Saluja; S. S. Pandya |
| Affiliations | Indukaka Ipcowala College of Pharmacy, New Vallabh Vidyanagar, Dist. Anand, Gujarat - 388 121; A.R.College of Pharmacy, Vallabh Vidyanagar, Dist. Anand, Gujarat - 388 120; Nutan Education Trust’s B. Pharmacy College, At. Rampura, Po. Kakanpur, Tal. Godhra, Dist. Panchmahal, Gujarat - 389 713, India |
| Corresponding author | shshukla@rediffmail.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 2, Issue 6 (2010) |
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