Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy ResearchVol. 2 | Issue 6 | 2010 | pp. 325–329Open access
Secondary metabolites and bioactivities of Myrtus communis
- 1*,
- 3,
- 1,
- 1,
- 3,
- 2
- 1 Departments of Chemistry of Natural Compounds
- 2 Pharmacology, National Research Centre, Dokki, Cairo, Egypt
- 3 Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt
Published in Pharmacognosy Research
Correspondence: Mahmoud I. Nassar
Departments of Chemistry of Natural Compounds
Email: mnassar_eg@yahoo.com
Copyright: © 2010 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2010
- Received:
- Aug 22, 2010
- Accepted:
- Jan 12, 2011
How to cite
Nassar, M. I., Aboutabl, E. S. A., Ahmed, R. F., El-Khrisy, E. D. A., Ibrahim, K. M., & Sleem, A. A. (2010). Secondary metabolites and bioactivities of Myrtus communis. Pharmacognosy Research, 2(6), 325–329. https://doi.org/10.4103/0974-8490.75449
Abstract
Background
Myrtus species are characterized by the presence of phenolic acids, flavonoids, tannins, volatile oils and fatty acids. They are remedies for variety of ailments. This study therefore investigated medicinal effects of Myrtus communis L.
Methods
Bioactivity studies of Myrtus communis L. leaves were carried out on volatile oil, 7% methanol and aqueous extracts and the isolated compounds myricetin 3-O-β-glucopyranoside, myricetin 3-O-∝-rhamnopyranoside and gallic acid.
Results
Determination of the median lethal dose (LD50) revealed that the volatile oil, alcoholic and aqueous extracts were practically nontoxic and highly safe as no lethality was observed. The tested materials (volatile oil, alcoholic and aqueous extracts, myricetin 3-O-β-glucopyranoside, myricetin 3-O-∝-rhamnopyranoside and gallic acid) showed significant antihyperglycemic, anti-inflammatory and antinociceptive effects as compared with control groups and reference drugs.
Conclusion
Administration of extracts of M. communis leaves could be safe at the dose used in this study.
Keywords
Subject
Article metadata
| Title | Secondary metabolites and bioactivities of Myrtus communis |
|---|---|
| Authors | Mahmoud I. Nassar; El-Sayed A. Aboutabl; Rania F. Ahmed; Ezzel-Din A. El-Khrisy; Khaled M. Ibrahim; Amany A. Sleem |
| Affiliations | Departments of Chemistry of Natural Compounds; Pharmacology, National Research Centre, Dokki, Cairo, Egypt; Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, Egypt |
| Corresponding author | mnassar_eg@yahoo.com |
| Journal | Pharmacognosy Research |
| Volume / Issue | Vol. 2, Issue 6 (2010) |
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