Isolation of forskolin from stem of Coleus forskohlii

Saleem, A.M.; Dhasan, P.B.; Rafiullah, M.R.M.

Research ArticlePharmacognosy MagazineVol. 1 | Issue 3 | 2005 | pp. 89–90Open access

Isolation of forskolin from stem of Coleus forskohlii

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³,
⁴

¹ Department of Pharmacognosy, C.L.Baid Metha College of Pharmacy, Thoraippakkam, Chennai 600096, India.
² School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan R.O.C.
³ Department of Siddha Medicine, Tamil University, Thanjavur 613500, India.
⁴ Faculty of Pharmacy, Hamdard University, New Delhi 110062, India.

Correspondence: A.M. Saleem
Department of Pharmacognosy, C.L.Baid Metha College of Pharmacy, Thoraippakkam, Chennai 600096, India.; School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan R.O.C.

Published:: Jan 1, 2005

How to cite

Saleem, A., Dhasan, P., & Rafiullah, M. (2005). Isolation of forskolin from stem of Coleus forskohlii. Pharmacognosy Magazine, 1(3), 89–90.

Abstract

Forskolin was isolated from the stem of Coleus forskohlii. Chloroform extract of the powdered stem was subjected to silica gel column chromatography to obtain crude forskolin. The crude forskolin was crystallized using ethyl acetate and n-hexane to obtain pure forskolin. The forskolin isolated was characterized by using UV, IR, ESI-Mass, 1H and 13C NMR. The yield was 0.103% w/w based on the dry weight of stem powder. The present study reconfirmed existing data on physical and spectroscopic characterization of forskolin.

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Article metadata

Title	Isolation of forskolin from stem of Coleus forskohlii
Authors	A.M. Saleem; P.B. Dhasan; M.R.M. Rafiullah
Affiliations	Department of Pharmacognosy, C.L.Baid Metha College of Pharmacy, Thoraippakkam, Chennai 600096, India.; School of Pharmacy, College of Medicine, National Taiwan University, Taipei 100, Taiwan R.O.C.; Department of Siddha Medicine, Tamil University, Thanjavur 613500, India.; Faculty of Pharmacy, Hamdard University, New Delhi 110062, India.
Journal	Pharmacognosy Magazine
Volume / Issue	Vol. 1, Issue 3 (2005)