Antitumoral Effect of Lawsonia inermis Extract on Melanoma Tumor‑bearing C57BL/6 Mice

Background: The genus <em>Cissus</em> (Vitaceae) is known for its medicinal properties. <em>Cissus quadrangularis</em> is a well-known medicinal plant, but other species are less explored. Objective: To evaluate the antioxidant and anti-inflammatory activities of <em>Cissus arnottiana</em>. Materials and Methods: The antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging, ferric reducing antioxidant power (FRAP), and total antioxidant capacity assays. The anti-inflammatory activity was evaluated using the protein denaturation inhibition assay and the membrane stabilization assay. Results: The methanolic extract of <em>C. arnottiana</em> showed significant antioxidant activity in all the assays. It also exhibited potent anti-inflammatory activity by inhibiting protein denaturation and stabilizing the red blood cell membrane. Conclusion: The results suggest that <em>C. arnottiana</em> has significant antioxidant and anti-inflammatory potential, which could be attributed to the presence of phytochemicals like flavonoids and phenolic compounds.