Open access · Peer reviewed · No APCs
Short CommunicationPharmacognosy MagazineVol. 2 | Issue 6 | 2006 | pp. 130–132Open access
Changes in the regional protein metabolism in the central nervous system (CNS) of diabetic rats: Protection by Cichorium intybus (Chicory)
- 1,2,3*,
- 1,2,3,
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- 1 Dept. of Pharmacognosy, Al-Ameen College of Pharmacy, Bangalore, 560 027, India.
- 2 Dept. of Zoology, Bangalore University, Bangalore 560 056, India.
- 3 King Abdul Aziz hospital, Jeddah, Kingdom of Saudi Arabia.
Published in Pharmacognosy Magazine
Correspondence: Nayeemunnisa Nayeemunnisa
Dept. of Pharmacognosy, Al-Ameen College of Pharmacy, Bangalore, 560 027, India.; Dept. of Zoology, Bangalore University, Bangalore 560 056, India.; King Abdul Aziz hospital, Jeddah, Kingdom of Saudi Arabia.
Email: nayeema201@yahoo.com
Copyright: © 2006 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2006
How to cite
Nayeemunnisa, N., R, N., & C, J. (2006). Changes in the regional protein metabolism in the central nervous system (CNS) of diabetic rats: Protection by Cichorium intybus (Chicory). Pharmacognosy Magazine, 2(6), 130–132.
Abstract
Protein content, ammonia and activity levels of Glutamate dehydrogenase (GDH) in the cerebrum, medulla oblongata of noarmal and alloxan – diabetic rats were measured. Protein content decreased in the regions of the brain studied during the diabetic state. Ammonia levels were also increased in the brain of alloxan diabetic rats. The activity level of glutamate dehydrogenase in the broad compartments of the brain was decreased during alloxan induced diabetes. Chicory offered marked protection, it brought down the levels of blood glucose and brain ammonia.
Keywords
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Article metadata
| Title | Changes in the regional protein metabolism in the central nervous system (CNS) of diabetic rats: Protection by Cichorium intybus (Chicory) |
|---|---|
| Authors | Nayeemunnisa Nayeemunnisa; Nawaz R; Jayashree C |
| Affiliations | Dept. of Pharmacognosy, Al-Ameen College of Pharmacy, Bangalore, 560 027, India.; Dept. of Zoology, Bangalore University, Bangalore 560 056, India.; King Abdul Aziz hospital, Jeddah, Kingdom of Saudi Arabia. |
| Corresponding author | nayeema201@yahoo.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 2, Issue 6 (2006) |
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