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Research ArticlePharmacognosy MagazineVol. 2 | Issue 7 | 2006 | pp. 172–173Open access
Isolation and Structure Elucidation of Aryltetralin Lignans from Linum tauricum ssp. bulgaricum
- 1,
- 1*
- 1 Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, 2 Dunav St, Sofia 1000, Bulgaria.
Published in Pharmacognosy Magazine
Correspondence: Iliana I. Ionkova
Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, 2 Dunav St, Sofia 1000, Bulgaria.
Email: ionkova@pharmfac.acad.bg
Copyright: © 2006 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2006
How to cite
Vasilev, N. P., & Ionkova, I. I. (2006). Isolation and Structure Elucidation of Aryltetralin Lignans from Linum tauricum ssp. bulgaricum. Pharmacognosy Magazine, 2(7), 172–173.
Abstract
A phytochemical investigation of the aerial parts of Linum tauricum ssp. bulgaricum (Linaceae) led to the isolation of five lignans using semi-preparative HPLC. LC-MS and NMR studies were used to characterize the structures of the isolated compounds. This is the first report of podophyllotoxin, 4′-demethylpodophyllotoxin, 4′-demethyl-6-methoxypodophyllotoxin and isolariciresinol in L. tauricum. Thus, the combination of semi-preparative HPLC, LC-MS and NMR techniques represents a powerful tool for unraveling the structure of naturally occurring lignans.
Keywords
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Article metadata
| Title | Isolation and Structure Elucidation of Aryltetralin Lignans from Linum tauricum ssp. bulgaricum |
|---|---|
| Authors | Nikolay P. Vasilev; Iliana I. Ionkova |
| Affiliations | Department of Pharmacognosy, Faculty of Pharmacy, Medical University-Sofia, 2 Dunav St, Sofia 1000, Bulgaria. |
| Corresponding author | ionkova@pharmfac.acad.bg |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 2, Issue 7 (2006) |
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