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Research ArticlePharmacognosy MagazineVol. 3 | Issue 10 | 2007 | pp. 101–102Open access
Hypoglycemic and Anti-hyperglycemic Effect of Alcoholic Extract of Benincasa hispida in Normal and in Alloxan Induced Diabetic Rats
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- 1 Pharmacognosy and Phytochemistry Division, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam- 530 003, India.
Published in Pharmacognosy Magazine
Correspondence: G. R. Battu
Pharmacognosy and Phytochemistry Division, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam- 530 003, India.
Email: sanjithmamidipalli@yahoo.co.in
Copyright: © 2007 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2007
How to cite
Battu, G. R., Mamidipalli, S. N., Parimi, R., Viriyala, R. K., Patchula, R. P., & Mood, L. R. (2007). Hypoglycemic and Anti-hyperglycemic Effect of Alcoholic Extract of Benincasa hispida in Normal and in Alloxan Induced Diabetic Rats. Pharmacognosy Magazine, 3(10), 101–102.
Abstract
The hypoglycemic and anti-hyperglycemic effect of alcoholic extract of Benincasa hispida was investigated in normal and alloxan induced diabetic rats. A single oral administration of alcoholic extract of Benincasa hispida at doses 50,100,200mg/kg produced a significant blood glucose reduction in a dose dependent manner. A bioguided extraction and fractionation of alcoholic extract of the stem of Benincasa hispida afforded three compounds, β-sitosterol, α-amyrin, quercetin. The alcoholic extract at 200mg/kg significantly reduced the blood glucose levels and equipotent with that of the standard drug Tolbutamide.
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Article metadata
| Title | Hypoglycemic and Anti-hyperglycemic Effect of Alcoholic Extract of Benincasa hispida in Normal and in Alloxan Induced Diabetic Rats |
|---|---|
| Authors | G. R. Battu; S. N. Mamidipalli; R. Parimi; R. K. Viriyala; R. P. Patchula; L. R. Mood |
| Affiliations | Pharmacognosy and Phytochemistry Division, University College of Pharmaceutical Sciences, Andhra University, Visakhapatnam- 530 003, India. |
| Corresponding author | sanjithmamidipalli@yahoo.co.in |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 3, Issue 10 (2007) |
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