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Research ArticlePharmacognosy MagazineVol. 3 | Issue 10 | 2007 | pp. 77–78Open access
Pharmacological effects of Trigonella foenum graecum Linn. seeds on various isolated perfused smooth muscle preparations
- 1*,
- 1
- 1 Department of Pharmacology and Environmental Toxicology, Dr. A.L.M. P.G. Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai – 600 113. Tamil Nadu, India.
Published in Pharmacognosy Magazine
Correspondence: Natarajan B.
Department of Pharmacology and Environmental Toxicology, Dr. A.L.M. P.G. Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai – 600 113. Tamil Nadu, India.
Email: natarajanphd@yahoo.com
Copyright: © 2007 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2007
How to cite
B., N., & R., D. (2007). Pharmacological effects of Trigonella foenum graecum Linn. seeds on various isolated perfused smooth muscle preparations. Pharmacognosy Magazine, 3(10), 77–78.
Abstract
In the present study, the pharmacological effects on different smooth muscles by the extracts like total alcoholic (TA), total aqueous (TQ), petroleum ether (PE), total alkaloidal (TK), total glycosidal (TG) and a phytochemical trigonelline (TR) from Trigonella foenum graecum Linn. seeds was investigated using isolated organ bath preparation method. 1 mg/ml dose of the extracts and the phytochemical showed significant anti-histaminic activity on guinea pig ileum, anti-cholinergic effect on rat colon and uterine stimulant activity on rat uterus. These results might be due the presence of some spasmolytic and spasmogenic constituents in the Trigonella foenum graecum Linn. (Fenugreek) seeds. These findings will help to invent some novel therapeutics from the fenugreek seeds.
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Article metadata
| Title | Pharmacological effects of Trigonella foenum graecum Linn. seeds on various isolated perfused smooth muscle preparations |
|---|---|
| Authors | Natarajan B.; Dhananjayan R. |
| Affiliations | Department of Pharmacology and Environmental Toxicology, Dr. A.L.M. P.G. Institute of Basic Medical Sciences, University of Madras, Taramani, Chennai – 600 113. Tamil Nadu, India. |
| Corresponding author | natarajanphd@yahoo.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 3, Issue 10 (2007) |
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