Study of antacid and diuretic activity of ash and extracts of Musa sapientum L. fruit peel.

The antacid and diuretic activity of different extracts and ash of peels of Musa sapientum L. (Musaceae) in rat was studied. The study suggested that the ash has good antacid activity. Diuretic study was carried out as per Lipschitz et al., (1943), where successive aqueous, ethanolic and petroleum ether extracts and ash of peel of fruit of Musa sapientum L. were studied for diuretic activity. The 6 hrs acute study of successive aqueous, ethanolic extracts and ash of the peel showed increase in urine volume and K+ ion excretion as compared to normal saline. Urinary levels of sodium, potassium (by flame photometry) and chloride (by titrimetry) were estimated. On the basis of observed results it is concluded that ash might have good antacid activity while successive ethanolic extract and ash exhibited evidence of diuretic potentials in normal rat in our experimental model. The histopathological examination and toxic effects on vital organs remained to be studied before their recommendation for use as diuretic agents.