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Research ArticlePharmacognosy MagazineVol. 4 | Issue 15 | 2008 | pp. 207–209Open access
Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes.
- 1*,
- 2,
- 2,
- 2,
- 2
- 1 Microbiology and Cell Biology Laboratory, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
- 2 Division of Pharmacognosy and PhytoChemistry, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
Published in Pharmacognosy Magazine
Correspondence: P Chattopadhyay
Microbiology and Cell Biology Laboratory, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.
Email: chatto_pronobesh@rediff.com
Copyright: © 2008 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2008
How to cite
Chattopadhyay, P., Wahi, A., Verma, N., Verma, A., & Aher, V. (2008). Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes. Pharmacognosy Magazine, 4(15), 207–209.
Abstract
Nitric oxide (NO) is generated in many mammalian tissues and is an important mediator of both physiological and pathological responses. The present study investigated the effect of alcoholic and aqueous extracts of whole plant of Phyllanthus fraternus Linn in NO production and platelets aggregation. Splenocytes were separated and NO production was measured. Both alcoholic and aqueous extracts showed significant increase in NO production and inhibition of platelets aggregation in chicken lymphocytes at a dose of 600 µg/ ml. The study reveals that P. fraternus may be used in asthma or in cardiovascular implications.
Keywords
Subject
Article metadata
| Title | Effect of Aqueous and Alcoholic Extracts of Phyllanthus fraternus Linn on Platelets Aggregation and Nitric Oxide Production in Chicken Lymphocytes. |
|---|---|
| Authors | P Chattopadhyay; A.K. Wahi; N Verma; A Verma; V.D. Aher |
| Affiliations | Microbiology and Cell Biology Laboratory, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India.; Division of Pharmacognosy and PhytoChemistry, College of Pharmacy, IFTM, Lodhipur Rajput , Moradabad- 244001 U.P.India, India. |
| Corresponding author | chatto_pronobesh@rediff.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 4, Issue 15 (2008) |
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