Open access · Peer reviewed · No APCs
Research ArticlePharmacognosy MagazineVol. 4 | Issue 16 | 2008 | pp. 273–274Open access
GC-MS and Bioactivity of the Essential Oil of Senecio rowleyanus Jacobs
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- 1 Department of Pharmacognosy, College of Pharmacy, Kasr El-Einy Street, 11562, Cairo University, Cairo, Egypt.
Published in Pharmacognosy Magazine
Correspondence: M. F. Yousif
Department of Pharmacognosy, College of Pharmacy, Kasr El-Einy Street, 11562, Cairo University, Cairo, Egypt.
Email: miriamyousif@hotmail.com
Copyright: © 2008 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2008
How to cite
Hawary, S. S. E., Galal, A. E., Yousif, M. F., & Kirollos, F. N. (2008). GC-MS and Bioactivity of the Essential Oil of Senecio rowleyanus Jacobs. Pharmacognosy Magazine, 4(16), 273–274.
Abstract
The chemical composition of the essential oil of Senecio rowleyanus Jacobs obtained by hydro distillation was analyzed by GC-MS and tested for cytotoxic and antimicrobial activities. Twenty five components representing 99.95% of the oil composition were identified. The oil was found to contain a significant amount of sesquiterpene alcohols of the guaiane type. Spathulenol (22.9%), germacrene B (12.4%), myrcene (12.8%) and viridiflorol (11%), were the predominant components. The oil exhibited marked cytotoxic activity against certain brain and liver human cell lines in vitro. In addition, it showed noticeable antimicrobial effect against the test microorganisms.
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Article metadata
| Title | GC-MS and Bioactivity of the Essential Oil of Senecio rowleyanus Jacobs |
|---|---|
| Authors | S. S. El Hawary; A. E. Galal; M. F. Yousif; F. N. Kirollos |
| Affiliations | Department of Pharmacognosy, College of Pharmacy, Kasr El-Einy Street, 11562, Cairo University, Cairo, Egypt. |
| Corresponding author | miriamyousif@hotmail.com |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 4, Issue 16 (2008) |
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