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Research ArticlePharmacognosy MagazineVol. 5 | Issue 19s | 2009 | pp. 74–77Open access
Bronchodilatory effect of Sphaeranthus indicus Linn against allergen induced bronchospasm in guinea pigs
- 1*,
- 1,
- 1
- 1 Department of Pharmacognosy, Smt.Saradchandrika Suresh Patil College of Pharmacy, Chopda, Jalgaon.
Published in Pharmacognosy Magazine
Correspondence: R. V. Sarpate
Department of Pharmacognosy, Smt.Saradchandrika Suresh Patil College of Pharmacy, Chopda, Jalgaon.
Email: rupali_sarpate@yahoo.co.in
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Mar 6, 2009
- Accepted:
- Jun 6, 2009
How to cite
Sarpate, R. V., Deore, T. K., & Tupkari, S. V. (2009). Bronchodilatory effect of Sphaeranthus indicus Linn against allergen induced bronchospasm in guinea pigs. Pharmacognosy Magazine, 5(19s), 74–77.
Abstract
The methanolic extract of whole plant of Sphaeranthus indicus Linn and its various fractions were tested for their bronchodilatory effect against histamine induced acute bronchospasm in guinea pigs. The methanolic extract and its fractions viz. petroleum ether, benzene, chloroform and ethyl acetate exhibited significant protection against bronchospasm, induced by histamine in guinea pigs. However significant (p<0.001) protection was exhibited by methanolic extract which was comparable with Chlorophenarmine maleate (2mg/kg) included as the standard in the study. The results of present study suggest that, the plant Sphaeranthus indicus shows the bronchodilatory activity.
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Article metadata
| Title | Bronchodilatory effect of Sphaeranthus indicus Linn against allergen induced bronchospasm in guinea pigs |
|---|---|
| Authors | R. V. Sarpate; T. K. Deore; S. V. Tupkari |
| Affiliations | Department of Pharmacognosy, Smt.Saradchandrika Suresh Patil College of Pharmacy, Chopda, Jalgaon. |
| Corresponding author | rupali_sarpate@yahoo.co.in |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 5, Issue 19s (2009) |
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