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Research ArticlePharmacognosy MagazineVol. 5 | Issue 19s | 2009 | pp. 90–92Open access
A Pentacyclic Triterpenoid Possessing Analgesic Activity from the Fruits of Dregea volubilis
- 1*,
- 2,
- 3,
- 4
- 1 Bengal Institute of Pharmaceutical Sciences, Kalyani, Nadia-741 235, West Bengal, India.
- 2 BCDA College of Pharmacy & Technology, Barasat, Kolkata-700 127, West Bengal, India.
- 3 Bengal School of Technology, Delhi Road, Sugandha, Dt. Hooghly, PIN: 712 102, West Bengal, India.
- 4 Division of Pharmacology, Dept. of Pharmaceutical Technology, Jadavpur University, Kolkata- 700 032, West Bengal, India.
Published in Pharmacognosy Magazine
Correspondence: Ma Biswas
Bengal Institute of Pharmaceutical Sciences, Kalyani, Nadia-741 235, West Bengal, India.
Email: moulisha_biswas@yahoo.co.in
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Mar 25, 2009
- Accepted:
- Jun 6, 2009
How to cite
Biswas, M., Biswas, K., Ghosh, A., & Haldar, P. (2009). A Pentacyclic Triterpenoid Possessing Analgesic Activity from the Fruits of Dregea volubilis. Pharmacognosy Magazine, 5(19s), 90–92.
Abstract
Fruits of Dregea volubilis were extracted by petroleum ether and subjected to column chromatography for obtaining the pure compound. The structure was determined on the basis of IR, MASS, NMR (PMR, CMR and DEPT) spectroscopic analysis. The compound was screened for analgesic activity in swiss albino mice by inducing writhing reflex with acetic acid. The petroleum ether extract of the fruits of Dregea volubilis Benth led to isolation of a pentacyclic triterpenoid designated as taraxerol and characterized as D- friedoolean- 14- en, 3 ol (Fig.1). In vitro analgesic activity has been shown by the isolated taraxerol. The compound taraxerol obtained from the petroleum ether extract of the fruits of Dregea volubilis showed analgesic activity in swiss albino mice.
Keywords
Subject
Article metadata
| Title | A Pentacyclic Triterpenoid Possessing Analgesic Activity from the Fruits of Dregea volubilis |
|---|---|
| Authors | Ma Biswas; Kb Biswas; AKc Ghosh; PKd Haldar |
| Affiliations | Bengal Institute of Pharmaceutical Sciences, Kalyani, Nadia-741 235, West Bengal, India.; BCDA College of Pharmacy & Technology, Barasat, Kolkata-700 127, West Bengal, India.; Bengal School of Technology, Delhi Road, Sugandha, Dt. Hooghly, PIN: 712 102, West Bengal, India.; Division of Pharmacology, Dept. of Pharmaceutical Technology, Jadavpur University, Kolkata- 700 032, West Bengal, India. |
| Corresponding author | moulisha_biswas@yahoo.co.in |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 5, Issue 19s (2009) |
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