Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy MagazineVol. 8 | Issue 30 | 2012 | pp. 141–148Open access
The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model
- 2,3*,
- 3,
- 4,5,
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- 1 Departments of, University, 830011 Urumqi, Xinjiang People’s Republic of China.
- 2 Drug Analysis.
- 3 Traditional Uighur Medicine and.
- 4 Pharmacology, Xinjiang Medical University, 830011 Urumqi, Xinjiang People’s Republic of China.
- 5 Department of Pharmacology, University Victor Segalen Bordeaux 2, 33076 Bordeaux, France.
Published in Pharmacognosy Magazine
Correspondence: Ainiwaer Aikemu
Drug Analysis.; Traditional Uighur Medicine and.
Copyright: © 2012 Manuscript Technomedia. This is an open access article.
- Published:
- May 23, 2012
- Received:
- Aug 15, 2011
How to cite
Aikemu, A., Yusup, A., Umar, A., Berké, B., Moore, N., & Upur, H. (2012). The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model. Pharmacognosy Magazine, 8(30), 141–148. https://doi.org/10.4103/0973-1296.96568
Abstract
Aim: This study was designed to study the antitumor and antioxidant activity of Uighur medicine abnormal savda munziq (ASMq) in the S180 and Ehrlich ascites carcinoma mice tumor model. Materials and Methods: The serum levels of superoxide dismutase (SOD), malonaldehyde (MDA), and glutathione-catalase (GSH-PX) were analyzed, and the mice were also subjected to a hypoxia tolerance test. Their climbing ability was also analyzed. Results: The findings of the study revealed that ASMq-treatment leads to an increase in blood serum SOD and GSH-PX levels but a decrease in blood serum MDA levels. Moreover, ASMq-treatment enhanced the survival time of mice maintained under hypoxic conditions and improved their mice climbing ability. Conclusions: The results of this study indicate that ASMq has obvious antitumor and antioxidative effects.
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Article metadata
| Title | The impact of the Uighur medicine abnormal savda munziq on antitumor and antioxidant activity in a S180 and Ehrlich ascites carcinoma mouse tumor model |
|---|---|
| Authors | Ainiwaer Aikemu; Abdiryim Yusup; Anwar Umar; Bénédicte Berké; Nicholas Moore; Halmurat Upur |
| Affiliations | Departments of, University, 830011 Urumqi, Xinjiang People’s Republic of China.; Drug Analysis.; Traditional Uighur Medicine and.; Pharmacology, Xinjiang Medical University, 830011 Urumqi, Xinjiang People’s Republic of China.; Department of Pharmacology, University Victor Segalen Bordeaux 2, 33076 Bordeaux, France. |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 8, Issue 30 (2012) |
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