A Comparative in vitro Evaluation of Antibacterial Efficacy of Different Dentifrices against Streptococcus mutans

Prasanth, Santhosh; Elango, Akshitha; Kamath, Dinesh Govinda; Thachanat, Arjun Rupesh; J, Jitha; Ali, Anzil KS

doi:10.5530/ajbls.2024.13.104

Research ArticleAsian Journal of Biological and Life SciencesVol. 13 | Issue 3 | 2026 | pp. 873–880Open access

A Comparative in vitro Evaluation of Antibacterial Efficacy of Different Dentifrices against Streptococcus mutans

¹,
²,
³,
⁴,
⁵,
⁶

¹ Department of Pediatric Dentistry, Government Dental College, Thiruvananthapuram, Kerala, INDIA.
² Department of Public Health Dentistry, Nandha Dental College and Hospital, Erode, Tamil Nadu, INDIA.
³ Department of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental Sciences, Kothamangalam, Kerala, INDIA.
⁴ Kuruvilla Memorial Dental Clinic, Thrissur, Kerala, INDIA.
⁵ Department of Conservative Dentistry and Endodontics, Sri Sankara Dental College, Akathumuri, Varkala, Kerala, INDIA.
⁶ Department of Public Health Dentistry, Royal Dental College, Kerala, INDIA.

Correspondence: Anzil KS AliEmail: anzilksali@gmail.com

Published:: Aug 17, 2026
Received:: Oct 2, 2024
Accepted:: Nov 28, 2024
DOI:: 10.5530/ajbls.2024.13.104

How to cite

Prasanth, S., Elango, A., Kamath, D. G., Thachanat, A. R., J, J., & Ali, A. K. (2026). A Comparative in vitro Evaluation of Antibacterial Efficacy of Different Dentifrices against Streptococcus mutans. Asian Journal of Biological and Life Sciences, 13(3), 873–880. https://doi.org/10.5530/ajbls.2024.13.104

Abstract

Aim: The in vitro study was conducted to determine the antibacterial efficiency of commercially accessible dentifrices against strains of S. mutans. Materials and Methods: The study assessed the 5 commercially accessible toothpastes and designated as M, C, TA, X and PE. The strain of S. mutans MTCC 890 was utilized and the agar well diffusion technique was employed to assess antibacterial effectiveness. Results: Group TA exhibits the highest average diameter against S. mutans, measuring 28.37±1.72 (24 hr) and 29.36±1.27 (48 hr). Group M exhibited the minimal zone of inhibition, measuring 23.25±0.43 at 24 hr and 23.14±0.74 at 48 hr. Conclusion: The evaluated toothpaste was efficacious against S. mutans at 24 and 48 hr; Group TA containing 1450 ppm of sodium fluoride was superior in inhibiting S. mutans and Group M had minimal efficacy.

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Article metadata

Title	A Comparative in vitro Evaluation of Antibacterial Efficacy of Different Dentifrices against Streptococcus mutans
Authors	Santhosh Prasanth; Akshitha Elango; Dinesh Govinda Kamath; Arjun Rupesh Thachanat; Jitha J; Anzil KS Ali
Affiliations	Department of Pediatric Dentistry, Government Dental College, Thiruvananthapuram, Kerala, INDIA.; Department of Public Health Dentistry, Nandha Dental College and Hospital, Erode, Tamil Nadu, INDIA.; Department of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental Sciences, Kothamangalam, Kerala, INDIA.; Kuruvilla Memorial Dental Clinic, Thrissur, Kerala, INDIA.; Department of Conservative Dentistry and Endodontics, Sri Sankara Dental College, Akathumuri, Varkala, Kerala, INDIA.; Department of Public Health Dentistry, Royal Dental College, Kerala, INDIA.
Corresponding author	anzilksali@gmail.com
Journal	Asian Journal of Biological and Life Sciences
Volume / Issue	Vol. 13, Issue 3 (2026)