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Original ArticlePharmacognosy MagazineVol. 12 | Issue 46s | 2016 | pp. S228–S230Open access
Life Span and Motility Effects of Ethanolic Extracts from Sophora moorcroftiana Seeds on Caenorhabditis elegans
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- 1 Department of Immunology, School of Basic Medical Sciences, China.
- 2 Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou University, China.
- 3 Department of Microbiology, Medical College, Northwest University for Nationalities, Lanzhou 730000, China.
Published in Pharmacognosy Magazine
Correspondence: Xingming Ma
Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou University, China.; Department of Microbiology, Medical College, Northwest University for Nationalities, Lanzhou 730000, China.
Email: maxm@lzu.edu.cn
Correspondence: Kaizhong Dong
Email: dkz@xbmu.edu.cn
Copyright: © 2016 Manuscript Technomedia. This is an open access article.
- Published:
- May 11, 2016
- Received:
- May 21, 2015
How to cite
Li, X., Han, J., Zhu, R., Cui, R., Ma, X., & Dong, K. (2016). Life Span and Motility Effects of Ethanolic Extracts from Sophora moorcroftiana Seeds on Caenorhabditis elegans. Pharmacognosy Magazine, 12(46s), S228–S230. https://doi.org/10.4103/0973-1296.182152
Abstract
Background: Sophora moorcroftiana is an endemic shrub species with a great value in folk medicine in Tibet, China. In this study, relatively little is known about whether S. moorcroftiana is beneficial in animals’ nervous system and life span or not. Materials and Methods: To address this question, under survival normal temperature (25°C), S. moorcroftiana seeds were extracted with 95% ethanol, and Caenorhabditis elegans were exposed to three different extract concentrations (100 mg/L, 200 mg/L, and 400 mg/mL) from S. moorcroftiana seeds. Results: The 95% ethanolic extracts from S. moorcroftiana seeds could increase life span and slow aging‑related increase in C. elegans and could not obviously influence the motility of C. elegans. Conclusion: Given these results by our experiment for life span and motility with 95% ethanolic extracts from S. moorcroftiana seeds in C. elegans, the question whether S. moorcroftiana acts as an anti‑aging substance in vivo arises.
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Article metadata
| Title | Life Span and Motility Effects of Ethanolic Extracts from Sophora moorcroftiana Seeds on Caenorhabditis elegans |
|---|---|
| Authors | Xin Li; Junxian Han; Rongyan Zhu; Rongrong Cui; Xingming Ma; Kaizhong Dong |
| Affiliations | Department of Immunology, School of Basic Medical Sciences, China.; Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou University, China.; Department of Microbiology, Medical College, Northwest University for Nationalities, Lanzhou 730000, China. |
| Corresponding author | maxm@lzu.edu.cn |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 12, Issue 46s (2016) |
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