Open access · Peer reviewed · No APCs
Original ArticlePharmacognosy MagazineVol. 16 | Issue 69 | 2020 | pp. 343–346Open access
Effects of the Japanese Kampo Medicine, Rikkunshito, on Gastrointestinal Motility Functions
- 1,
- 2,
- 2*
- 1 Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University, Seoul.
- 2 Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan, Korea.
Published in Pharmacognosy Magazine
Correspondence: Byung Joo Kim
Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan, Korea.
Email: vision@pusan.ac.kr
Copyright: © 2020 Manuscript Technomedia. This is an open access article.
- Published:
- Jun 15, 2020
- Received:
- Sep 18, 2019
- Accepted:
- Dec 26, 2019
- DOI:
- 10.4103/pm.pm_370_19
How to cite
Hwang, M., Han, D., & Kim, B. J. (2020). Effects of the Japanese Kampo Medicine, Rikkunshito, on Gastrointestinal Motility Functions. Pharmacognosy Magazine, 16(69), 343–346. https://doi.org/10.4103/pm.pm_370_19
Abstract
Objectives: The objective was to find the effect of GI motility with Rikkunshito. Materials and Methods: The prokinetic effect of Rikkunshito was investigated by studying the gastric emptying (GE) and intestinal transit rate (ITR) or experimentally induced GI motility dysfunction (GMD). Results: The oral administration of Rikkunshito significantly increased GE and ITR and restored the delayed GE and ITR. Its effect was similar to that of conventional prokinetics, such as domperidone and mosapride. Moreover, we made the mouse GMD models, such as acetic acid or streptozotocin, and ITR had shown a great decrease. This decrease was recovered by Rikkunshito. Conclusion: Rikkunshito revealed its prokinetic effect through an increase of GE and ITR. We found a great possibility of Rikkunshito for the GI control drug.
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Article metadata
| Title | Effects of the Japanese Kampo Medicine, Rikkunshito, on Gastrointestinal Motility Functions |
|---|---|
| Authors | Minwoo Hwang; Donghun Han; Byung Joo Kim |
| Affiliations | Department of Sasang Constitutional Medicine, College of Korean Medicine, Kyung Hee University, Seoul.; Division of Longevity and Biofunctional Medicine, School of Korean Medicine, Pusan National University, Yangsan, Korea. |
| Corresponding author | vision@pusan.ac.kr |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 16, Issue 69 (2020) |
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