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Original ArticlePharmacognosy MagazineVol. 15 | Issue 62s | 2019 | pp. S34–S37Open access
In vitro Antileishmanial Activity of Methanolic Extracts for Some Selected Medicinal Plants
- 2,3*,
- 3,4,
- 3,
- 3,
- 3
- 1 Department of Biochemistry, Faculty of Agriculture, Minia University.
- 2 Department of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University.
- 3 Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
- 4 Department of Natural Products Chemistry, Faculty of Pharmacy, Yasuda Women’s University, Hiroshima, Japan.
Published in Pharmacognosy Magazine
Correspondence: Ahmed Gomaa Gomaa Darwish
Department of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.
Email: ahmed.darwish@famu.edu
Copyright: © 2019 Manuscript Technomedia. This is an open access article.
- Published:
- Apr 26, 2019
- Received:
- Nov 16, 2018
- DOI:
- 10.4103/pm.pm_570_18
How to cite
Darwish, A. G. G., Samy, M. N., Sugimoto, S., Matsunami, K., & Otsuka, H. (2019). In vitro Antileishmanial Activity of Methanolic Extracts for Some Selected Medicinal Plants. Pharmacognosy Magazine, 15(62s), S34–S37. https://doi.org/10.4103/pm.pm_570_18
Abstract
Objective: The aim of this study is to evaluate the antileishmanial activity of selected medicinal plants; ten well‑known medicinal plants cultivated and growing under African environmental conditions were studied. Materials and Methods: The methanolic extracts of these plants were screened for their antileishmanial activity against Leishmania major using 3‑(4.5‑dimethylthiazol‑2yl)‑2.5‑diphenyltetrazolium bromide assay. Results: The methanol extract of Colchicum autumnale and Alpinia officinarum showed potent antileishmanial activity at inhibition% value of 98.29% ± 0.75% and 97.25 ± 1.63%, respectively, while Silybum marianum exhibited inhibition% value of 90.97% ± 1.13%, compared with the standard amphotericin B (89.31% ± 2.08%). Conclusion: Considering these results, medicinal plants from African environment could constitute a developer source for antileishmanial compounds.
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Article metadata
| Title | In vitro Antileishmanial Activity of Methanolic Extracts for Some Selected Medicinal Plants |
|---|---|
| Authors | Ahmed Gomaa Gomaa Darwish; Mamdouh Nabil Samy; Sachiko Sugimoto; Katsuyoshi Matsunami; Hideaki Otsuka |
| Affiliations | Department of Biochemistry, Faculty of Agriculture, Minia University.; Department of Pharmacognosy, Graduate School of Biomedical and Health Sciences, Hiroshima University.; Department of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia, Egypt.; Department of Natural Products Chemistry, Faculty of Pharmacy, Yasuda Women’s University, Hiroshima, Japan. |
| Corresponding author | ahmed.darwish@famu.edu |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 15, Issue 62s (2019) |
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