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Research ArticlePharmacognosy MagazineVol. 4 | Issue 15 | 2008 | pp. 193–194Open access
Antiulcer and antimicrobial activities of Stryphnodendron rotundifolium Mart.
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- 1 Laboratório de Pesquisas de Produtos Naturais, Departamento de Química Biológica, Universidade Regional do Cariri, Rua Cel. Antônio Luiz, 1161, CEP 63105-000, Crato – Ceará, Brazil.
Published in Pharmacognosy Magazine
Correspondence: José Galberto Martins da Costa
Laboratório de Pesquisas de Produtos Naturais, Departamento de Química Biológica, Universidade Regional do Cariri, Rua Cel. Antônio Luiz, 1161, CEP 63105-000, Crato – Ceará, Brazil.
Email: galberto@urca.br
Copyright: © 2008 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2008
How to cite
Rodrigues, F. F. G., Cabral, B. D. S., Coutinho, H. D. M., Cardoso, A. L. H., Campos, A. R., & Costa, J. G. M. D. (2008). Antiulcer and antimicrobial activities of Stryphnodendron rotundifolium Mart. Pharmacognosy Magazine, 4(15), 193–194.
Abstract
The ethanolic extract of Stryphnodendron rotundifolium stem bark (EESR) was investigated for therapeutic properties using ethanol-induced ulceration in mice. Antimicrobial and preliminary phytochemical screening of the extract was also investigated. The extract (200-400 mg/kg p.o.) dose dependently reduced ethanol (0.2 mL/animal p.o.) - induced ulceration in mice. EESR showed antimicrobial activity against five bacterial species (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Shigella flexineri, Staphylococcus epidermidis) but not against the fungi Aspergillus niger. The above results show that Stryphnodendron rotundifolium bark probably contains some active ingredients that could be developed for health problems as have been claimed by traditional popular use.
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Article metadata
| Title | Antiulcer and antimicrobial activities of Stryphnodendron rotundifolium Mart. |
|---|---|
| Authors | Fabiola Fernandes Galvão Rodrigues; Brisa do Svadesvich Cabral; Henrique Douglas Melo Coutinho; André Luiz Herzog Cardoso; Adriana Rolim Campos; José Galberto Martins da Costa |
| Affiliations | Laboratório de Pesquisas de Produtos Naturais, Departamento de Química Biológica, Universidade Regional do Cariri, Rua Cel. Antônio Luiz, 1161, CEP 63105-000, Crato – Ceará, Brazil. |
| Corresponding author | galberto@urca.br |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 4, Issue 15 (2008) |
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