Open access · Peer reviewed · No APCs
Research ArticlePharmacognosy MagazineVol. 5 | Issue 19s | 2009 | pp. 36–41Open access
Evaluation of Hypoglycemic and antihyperglycemic effects of alcoholic extract of Chonemorpha fragrans root in normal and alloxan induced diabetic rats
- 1*,
- 2,
- 1,
- 2,
- 1
- 1 Ultra College of Pharmacy, Madurai, Tamilnadu-20, India.
- 2 Sharadchandra Pawar College of Pharmacy, Otur, Pune, MS, 412409, India.
Published in Pharmacognosy Magazine
Correspondence: VS Shende
Ultra College of Pharmacy, Madurai, Tamilnadu-20, India.
Email: vikas_shende2003@yahoo.co.in
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 1, 2009
- Received:
- Jan 8, 2009
- Accepted:
- Jun 6, 2009
How to cite
Shende, V., Sawant, V., Turuskar, A., Chatap, V., & Vijaya, C. (2009). Evaluation of Hypoglycemic and antihyperglycemic effects of alcoholic extract of Chonemorpha fragrans root in normal and alloxan induced diabetic rats. Pharmacognosy Magazine, 5(19s), 36–41.
Abstract
In light of traditional claim of Chonemorpha fragrans in the treatment of diabetes were carryout evaluate its effect on rats. Alcoholic extract of Chonemorpha fragrans root (CF.alc.extract) administered orally at dose 100 mg/kg and 200mg/kg in different condition such as normal, glucose over loaded in normal rats, and alloxan induced diabetic rats. At dose 200 mg/kg per oral (p.o.) was produce significantly reduce blood glucose level in fasted normal rat and against glucose over loaded rats and alloxan induced diabetic rats at single dose as well as twelve day treatment. Histopathology studies on pancreas alloxan induced diabetic rats inflammatory changes were detected in pancreatic islets results from selectively destroy of insulin producing β-cells. These changes are dose-dependently inhibited by CF.alc.extract and gliclazide
Keywords
Subject
Article metadata
| Title | Evaluation of Hypoglycemic and antihyperglycemic effects of alcoholic extract of Chonemorpha fragrans root in normal and alloxan induced diabetic rats |
|---|---|
| Authors | VS Shende; VA Sawant; AO Turuskar; VK Chatap; C Vijaya |
| Affiliations | Ultra College of Pharmacy, Madurai, Tamilnadu-20, India.; Sharadchandra Pawar College of Pharmacy, Otur, Pune, MS, 412409, India. |
| Corresponding author | vikas_shende2003@yahoo.co.in |
| Journal | Pharmacognosy Magazine |
| Volume / Issue | Vol. 5, Issue 19s (2009) |
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- Occurrence of high levels of Cadmium, Mercury and Lead in Medicinal Plants of Indiapp. 15–18
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