Open access · Peer reviewed · No APCs
Pharmaceutical EducationIndian Journal of Pharmaceutical Education and ResearchVol. 47 | Issue 4 | 2014 | pp. 24–30Open access
In Vitro Antioxidant Activity and HPTLC Analysis of Borago Officinalis Linn.
- 1,
- 1,
- 1,
- 2,
- 1*
- 1 Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India-110062.
- 2 Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India-110062.
Published in Indian Journal of Pharmaceutical Education and Research
Correspondence: Sayeed Ahmad
Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India-110062.
Email: sahmad_jh@yahoo.com
Copyright: © 2014 Manuscript Technomedia. This is an open access article.
- Published:
- Jan 30, 2014
- DOI:
- 10.5530/ijper.47.4.4
How to cite
Singh, M., Kamal, Y. T., Khan, M. A., Parveen, R., & Ahmad, S. (2014). In Vitro Antioxidant Activity and HPTLC Analysis of Borago Officinalis Linn. Indian Journal of Pharmaceutical Education and Research, 47(4), 24–30. https://doi.org/10.5530/ijper.47.4.4
Abstract
Borage (Borago officinalis L.) is known drug in Unani system of medicine which is very popular as Gaozaban and used in various khamira (semi solid Unani formulations) for cardioprotection. In the present study, a comparative antioxidant potential of different extracts of borage leaves along with rosmarinic acid (positive marker of the drug) was carried out using DPPH and nitric oxide free radical scavenging method prior to estimated total phenolic content in each extract. The suitable solvent systems were developed for TLC profiling of each extract and results were compared. A HPTLC method was developed for the analysis of rosmarinic acid and it was validated as per the ICH guidelines. The developed method was found simple, selective, economic and accurate for the analysis of rosmarinic acid. The developed method was used for the estimation of rosmarinic acid in different extracts and it was concluded that content of rosmarinic acid is correlated to the antioxidant potential of the drug.
Keywords
Subject
Article metadata
| Title | In Vitro Antioxidant Activity and HPTLC Analysis of Borago Officinalis Linn. |
|---|---|
| Authors | Mhaveer Singh; Y. T. Kamal; M. A. Khan; Rabea Parveen; Sayeed Ahmad |
| Affiliations | Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India-110062.; Department of Pharmaceutics, Faculty of Pharmacy, Hamdard University, Hamdard Nagar, New Delhi, India-110062. |
| Corresponding author | sahmad_jh@yahoo.com |
| Journal | Indian Journal of Pharmaceutical Education and Research |
| Volume / Issue | Vol. 47, Issue 4 (2014) |
Also in this issue
- Objective Structured Clinical Examination in Pharm D and Clinical Pharmacy Courses in India; a Rising Need to Acquaint?pp. 1–6
- Rationality of Prescription Writingpp. 7–15
- Global Metadata Analysis of Research Publications in Pharmaceutical Sciencespp. 16–23
- Synthesis and preliminary evaluation of a focused chalcone library for anti-inflammatory activitypp. 31–48
- Development and Physicochemical, In Vitro and In Vivo Evaluation of Transdermal Patches of Zaleplonpp. 49–58
Readers Also Viewed
Effect of the Fractions of Coccinia grandis on Ethanol- Induced Cerebral Oxidative Stress in Rats
M. Umamaheswari, T. K. Chatterjee
Jan 1, 2009
Phytochemical Screening and Antioxidant Activity Evaluation of Selected Philippine Fruit Peels and Pulps
Mildred Dagcuta Pates, Angelo Mark Po Walag, Romeo M. Del Rosario
Aug 17, 2026
Impact of Artificial Intelligence Assisted Drug Therapy Optimization on Drug Related Problems Amongst Older Adult Patients: A Systematic Review
Jehath Syed, Christy Thomas, Bavneet Kaur
Oct 23, 2026