Open access · Peer reviewed · No APCs
Pharm AnalysisJournal of Young PharmacistsVol. 1 | Issue 4 | 2009 | pp. 359–363Open access
Quantitative Estimation of Efavirenz by High Performance Thin Layer Chromatography
- 1*,
- 1,
- 1
- 1 Department of Pharmaceutical Analysis, Prin. K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai, INDIA.
Published in Journal of Young Pharmacists
Correspondence: Hamrapurkar P
Department of Pharmaceutical Analysis, Prin. K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai, INDIA.
Email: phamrapurkar@gmail.com
Copyright: © 2009 Manuscript Technomedia. This is an open access article.
- Published:
- Dec 18, 2009
How to cite
P, H., M, P., & N, S. (2009). Quantitative Estimation of Efavirenz by High Performance Thin Layer Chromatography. Journal of Young Pharmacists, 1(4), 359–363. https://doi.org/10.4103/0975-1483.59328
Abstract
A simple, accurate, and precise HPTLC method has been developed and validated for the estimation of efavirenz from bulk drug and capsule formulations. The separation was achieved on TLC plates using an appropriate solvent system. The spots so developed were densometrically scanned at 247 nm. The linearity of the method was found to be within the concentration range of 1-40 µg/ml. The validation parameters, tested in accordance with the requirements of ICH guidelines, prove the suitability of this method. The method was successfully applied for determination of drug in capsules, wherein no interference from capsule excipients was observed, indicating the speciÞ city of the developed method. Thus, the proposed method can be used successfully for routine analysis of efavirenz from capsule and bulk formulations.
Keywords
Subject
Article metadata
| Title | Quantitative Estimation of Efavirenz by High Performance Thin Layer Chromatography |
|---|---|
| Authors | Hamrapurkar P; Phale M; Shah N |
| Affiliations | Department of Pharmaceutical Analysis, Prin. K. M. Kundnani College of Pharmacy, Jote Joy Building, Rambhau Salgaonkar Marg, Cuffe Parade, Colaba, Mumbai, INDIA. |
| Corresponding author | phamrapurkar@gmail.com |
| Journal | Journal of Young Pharmacists |
| Volume / Issue | Vol. 1, Issue 4 (2009) |
Also in this issue
- Effect of Permeation Enhancers on the Release and Permeation Kinetics of Oxytetracycline Hydrochloride Organogel Formulationspp. 285–289
- Microdosing vs. Therapeutic Dosing for Evaluation of Pharmacokinetic Data: A Comparative Studypp. 290–294
- Advanced PEGylation for the Development of Raloxifene Hydrochloride, BCS Class II Drugpp. 295–300
- Development and Evaluation of Sustained Delivery of Diclofenac Sodium from Hydrophilic Polymeric Beadspp. 301–304
- Design, Evaluation and Study of Effect of Hydrophilic Polymers on Release Rate of Antiulcer Floating Tabletspp. 305–311
Readers Also Viewed
Effect of the Fractions of Coccinia grandis on Ethanol- Induced Cerebral Oxidative Stress in Rats
M. Umamaheswari, T. K. Chatterjee
Jan 1, 2009
Phytochemical Screening and Antioxidant Activity Evaluation of Selected Philippine Fruit Peels and Pulps
Mildred Dagcuta Pates, Angelo Mark Po Walag, Romeo M. Del Rosario
Aug 17, 2026
Impact of Artificial Intelligence Assisted Drug Therapy Optimization on Drug Related Problems Amongst Older Adult Patients: A Systematic Review
Jehath Syed, Christy Thomas, Bavneet Kaur
Oct 23, 2026